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Take interest, I implore you, in those sacred dwellings called laboratories; demand that they be multiplied, that they be adorned. These are the temples of the future, temples of well-being and of happiness. - Louis Pasteur

The laboratory in buzz with routine diagnostic Mycology work supporting the 1500 bedded teritiary care hospital. Research work on pathogenesis and epidemiology of Basidiomycetous yeast, Fungal Dimorphism, Superficial mycoses.  The laboratory holds a good collection of fungi over 86 genera. 

Mycoses and Man - Are fungi a boon or a bane to mankind?

Fungal diseases have  become increasingly important in the past few years. Because few fungi are professional pathogens, fungal pathogenic mechanisms tend to be highly complex, arising in large part from adaptations of preexisting characteristics of the organisms nonparasitic lifestyles. In the past few years, genetic approached have elucidated many fungal virulence factors, and increasing knowledge host pathogenesis has grown correspondingly.

MANIPAL MYCOLOGY CULTURE COLLECTION (MMCC)

 

A case of Feline Lymphocutaneous Sporotrichosis confirmed with a murine model

62 year old retired male medical attendant, a native of Kudremukh was referred to the skin department with complaints of asymptomatic nodular swellings over the right forearm of two months duration

The patient attributed the development of lesions to flea bite from  domestic cat. There was no history of fever, joint pain or systemic complaints. There was no history of recent travel. History of gardening was present. The patient was a known hypertensive.

 

Cutaneous examination revealed  presence of firm, non tender, mobile nodular lesions over right elbow and forearm. A provisional diagnosis of foreign body granuloma was considered and an excision biopsy was done and histopathology was consistent with the diagnosis. He was treated with topical steroids.

 

On subsequent visit, three months later, the patient presented with development of multiple nodulo-ulcerative lesions in a linear distribution along the right forearm and arm. Lesions had also developed adjacent to the biopsy site. There was no lymphadenopathy and the skin and mucous membrane elsewhere on the body were normal. Systemic examination did not reveal any abnormality. Routine haematology and urine examination were within normal limits. A repeat excision biopsy was done and tissue bit was sent for fungal culture.